Borkware: Don't Forget VoodooPad.
"Some folks I know put everything into a single VoodooPad document and use it to store their life (or at least their brains). I typically have one VoodooPad document per project, which usually fall int into one of three broad categories:"
Mark Dalrymple's VoodooPad usage is a lot like what I do as well. It's always interesting to see how other folks use VoodooPad, and what industry they are in. Programmers for the most part use VoodooPad the way markd describes, students and researchers have their own little techniques, some folks use it to build websites and nothing else, and then there's the GTD crowd and their python and lua scripts flying around.
It's a never ending source of amusement to me.